Panadol Advance is an advanced formulation of paracetamol that contains Optizorb. Unlike some pain relievers that can sit in your stomach, Panadol Advance starts to release its medicine in as little as 5 minutes – and still has the safety profile you trust from Panadol. Panadol Advance is gentle on stomach when used as directed. The OPTIZORB Formulation contains a patented delivery system which allows it deliver paracetamol more efficiently by breaking down faster than regular Panadol tablets Other features:  The medicine in Panadol Advance is suitable for people at risk of stomach problems when taken as directed.